In small study, healthy lifestyle fights cell ageing | HEALTH - geo.tv
HEALTH AWARENESS WELFARE (HAW):
Healthy Lifestyle for Sound Health and Longevity
===========================================================
// PARIS:In a small but unprecedented study, scientists on Tuesday said they had
proof that a healthy lifestyle helps the body's cells fight ageing.
The strategy is structured around a whole-food, plant-based diet, moderate
daily exercise, yoga-based relaxation and stress management, they said.
Researchers recruited 35 men, 10 of whom were asked to follow this lifestyle, while
the other 25 were not asked to make any lifestyle changes at all.
In addition to the diet and daily physical and mental routines, the 10
also attended weekly sessions for three months where their new skills
were reinforced by specialists, including a one-hour weekly "support"
session.
After five years, the scientists assessed the participants for a hallmark of biological ageing called telomeres.
Telomeres are nubby pieces of protein that are attached to the end of
chromosomes. They help to protect the precious strings of DNA code when a
cell replicates.
They are often likened to the tips of shoelaces.As the telomere wears down, its protection erodes too, and so does the risk that the DNA is not faithfully replicated in the daughter cell, which boosts the risk of cellular malfunction and then disease,
including cancer.
Looking at the length of telomeres thus gives a telltale of cellular lifespan.
Among the 10-man group, telomere length increased significantly by an average
of 10 percent over the five years -- and it was higher among those who
had adhered most faithfully to the new lifestyle.
Among the "control" group, though, telomeres had shrunk by three percent on average.
The study has limitations as the number of recruits was small, and it was
conducted as part of an investigation into prostate cancer.
In addition, the research was not empowered to test whether lifestyle changes affected the risk of cancer.
But, say its authors, its focus on the vital telomeres was carried out scientifically and over the long term.
This is what makes it new compared with evidence that is anecdotal or only short-term.
"The implications of this relatively small pilot study may go beyond men
with prostate cancer," said Dean Ornish, a professor at the University
of California in San Francisco, who led the study.
"If validated by large-scale randomised controlled trials, these comprehensive
lifestyle changes may significantly reduce the risk of a wide variety of
diseases and premature mortality.
"Our genes, and our telomeres, are a predisposition, but they are not necessarily our fate."
Ornish is the founder of the not-for-profit Preventive Medicine Research
Institute at the university. He has vigorously promoted in medical
presentations and books the argument that lifestyle changes, especially a
shift in diet, can protect against disease.
The study appears in the journal The Lancet Oncology..........//
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